PROSTATITIS SYMPTOMS 

Prostatitis is a painful inflammation of the prostate. It is a common condition that can affect men of all ages.

Dawasanté experts provide you with a natural treatment based on medicinal plants to cure prostatitis permanently. 

HERBAL TREATMENT FOR PROSTATITIS

We have the right and ideal plants for healing prostatitis. They are used to slow the growth of the prostate, by reducing the "fuel" of prostate cells: benign prostatic hypertrophy and prostate cells work with the same factors and use the same "fuel". 

These plants are also effective when the volume of the prostate is visible, above 40 m. Obtaining their relaxation and promoting the opening of the funnel of the neck of the bladder and the prostatic urethra. They thus improve the emptying of the bladder. These plants are the first phytotherapeutic approach to reduce the frequency of urination and improve the spray.

To discover our remedy to cure prostatitis, click here!

To contact our experts please call or write to us on the following number, tel / WhatsApp
: +229 51374202

Acute bacterial prostatitis

Acute bacterial prostatitis is caused by bacteria. It is said to be acute because its symptoms appear suddenly and can be severe. It is the least common type of prostatitis, but the easiest to treat. 

Chronic bacterial prostatitis

Chronic (long-term) bacterial prostatitis is caused by bacteria and often persists for several months. Its symptoms are usually less severe than those caused by acute bacterial prostatitis and tend to go away and then come back. Chronic bacterial prostatitis can cause urinary symptoms like a burning sensation or pain during urination, but it does not cause fever or chills. It seems to occur more often in older men with benign prostatic hyperplasia.

This type of prostatitis is the most common. This is a chronic condition that is not caused by bacteria and causes pain or discomfort that may go away and return to the pelvis.

Asymptomatic inflammatory prostatitis

The prostatitis Asymptomatic inflammatory causes no symptoms and does not require treatment. Doctors often diagnose it when they do tests to check for other conditions, such as prostate cancer, or to determine the cause of infertility. To ask this

Prostatitis can cause the following signs and symptoms:

At first, prostate cancer does not cause any symptoms. Note that those shown below may be related to another prostate disease, such as benign prostatic hypertrophy.

• Difficulty urinating: difficulty starting to urinate or holding urine, inability to urinate, need to urinate frequently (especially at night), poor urine output, a burning sensation or pain when passing urine 'urinate.
• The blood in the urine or semen.
• Pain or frequent stiffness in the lower back, hips or upper thighs.
• Changes in urinary function: frequent urge, urge to urinate, need to push, urine retention, burning while urinating.
• Genital changes: painful ejaculations, or difficulty getting an erection. Predisposed people 

Note that some "  at-risk  " men will never get prostate cancer. Several risk factors are being studied.

• Age. In North America, prostate cancer mainly affects men over the age of 60. The average age at diagnosis is 70 years, and 80 years at the time of death. Younger, only 0.5% of prostate cancers appear before age 50, and 22% between 55 and 64 ...
• Family history. The risks are higher when the father or a brother has already suffered from this disease, which suggests a genetic predisposition. This hypothesis is reinforced by the discovery that carriers of the BRCA1 and BRCA2 genes have an increased risk of prostate cancer.
• Ethnic origin. Men of African descent are more at risk than Caucasians, who are more at risk than Asians. It is estimated that Indians and Chinese are about 50 times less affected by prostate cancer than Westerners. However, when they migrate to countries where the disease is more common, their risk also increases. This suggests that factors not only related to genes but also to diet exert an influence.
• Obesity:  A man who is significantly overweight has a higher risk of having prostate cancer detected at an advanced stage.
• Inflammation or infection of the prostate increases the risk of prostate cancer when it lasts a long time.
• Tall men have a higher risk of prostate cancer.
• Men who have been exposed to pesticides have a slightly higher risk of prostate cancer, especially if they have a history of prostate cancer in their family.
• Exposure to cadmium or rubber derivatives in the workplace also increases the risk of prostate cancer.

The prostatitis is sometimes the consequence of a sexual infection  (  sexually transmitted disease ). But very often, no triggering factor is found.

In the elderly, prostatitis is frequently the consequence of a urinary infection, itself secondary to an enlarged prostate which promotes urinary stasis. We then speak of adenomitis

• presence of blood in the urine (hematuria) or semen
• burning sensation or pain during urination
• difficult or painful ejaculation
• urethral discharge
• pain or discomfort in the genitals, groin, lower abdomen, or lower back
• pain or feeling of pressure in the rectum
• need to urinate often (frequent urination)
• very urgent need to urinate (urgent urination)
• reduced urine stream
• difficulty urinating
• fever, chills, and muscle pain
• recurrent urinary tract infections
• sexual problems and loss of libido

.

More precisely:

• Fever over 38.5,  chills,  severe fatigue  ; 
• The patient complains of  burning while urinating, of having  difficulty urinating  (  dysuria ), of urinating too often  (pollakiuria); 
• Sometimes there is a  purulent discharge  from the urinary meatus;
• Presence of blood in urine or semen;  
• The urine may be cloudy and smelly.

Acute prostatitis can present with  flu-like signs  :

•  Diffuse muscle pain, joint pain …; 
• Rarely, a  sensation of a foreign body in the anus is associated.

Still talking about this disease chronic prostatitis is characterized by chronic perineal pain, sometimes in the anal area. Voiding burns can evolve for several years.

Most often, prostate cancer does not have any symptoms; it is said to be "silent". It will be discovered by chance, following a blood test or during a routine prostate exam. In this case, the doctor will have performed a digital rectal examination, noted induration, and he will have sounded the alarm. This hardening is the most frequent clinical sign.

Similar symptoms when the urethra is compressed

Symptoms start to appear when the tumor grows and puts pressure on the urethra or when it is advanced. The symptoms are the same as for benign prostatic hypertrophy (BPH), because as we age the prostate increases in size and compresses the urethra. Prostatitis can also cause symptoms similar to prostate cancer. On the other hand, as mentioned earlier, the majority of patients with prostate cancer will have no clinical symptoms.

After the age of 40, it is important that people make sure not to confuse  BPH,  prostatitis and prostate cancer. The examination by a doctor therefore becomes more than important to be clear about it.

BPH or large prostate

The most common signs and symptoms

In the early stages of BPH, there are no signs and symptoms. These appear when the enlarged prostate puts pressure on the urethra and bladder. This can reduce the diameter of the urethra (compress it) or irritate the bladder, which can cause changes in urinary habits and difficulty passing urine. In some patients, symptoms may appear with minimal enlargement of the prostate.

BPH can cause the following symptoms:

• A need to urinate often day and night (frequent urination)
• An urgent need to urinate (urgent urination)
• Difficulty starting or stopping urinating
• A weak or slow urine stream
• A stream of urine that stops
• A feeling of not emptying your bladder
• Difficulty controlling your bladder (urine leakage)
• Pain or burning sensation when urinating
• Difficult or painful ejaculation
• Presence of blood in urine or semen (rare)

Prostatitis or inflammation of the prostate

The most common signs and symptoms

Prostatitis can cause a wide range of symptoms that vary from one man to another. They can be similar to those caused by benign prostatic hyperplasia (BPH) and prostate cancer. On the other hand, it is distinguished by the presence of pain in the pelvic region and so acute, by high fever and chills.

Prostatitis can be caused by an acute urinary tract infection (bacterial prostatitis) or by chronic inflammation / chronic tenderness.

Prostatitis can cause the following symptoms:

• A need to urinate often day and night (frequent urination)
• An urgent need to urinate (urgent urination)
• Difficulty starting or stopping urinating
• A weak or slow urine stream
• A stream of urine that stops
• A feeling of not emptying your bladder
• Pain or burning sensation when urinating
• Pain in the pelvis area (genitals, groin, lower abdomen or lower back)
• Difficult or painful ejaculation
• Fever and chills if the prostatitis is acute
• Recurrent urinary tract infections
• Presence of blood in urine or semen (rare)

BPH and prostatitis do not equate to prostate cancer. They are among the most common diseases related to the prostate.

Localized cancer

Signs and symptoms of localized cancer

The most common signs and symptoms

It is common for prostate cancer in its very early stages to not cause any symptoms due to its generally slow development. Symptoms can appear if the tumor grows and compresses your urethra - causing changes in your urinary habits or other problems - or if your cancer is advanced. The tumor does not usually cause pain in the prostate itself.

As mentioned above, it should be remembered that all of these symptoms are usually caused by benign enlargement of the prostate that occurs with age and not by prostate cancer. They can also be caused by other problems related to the urinary tract, including bacterial or infectious prostatitis, among others.

Cancer can cause the following symptoms (most often there are no symptoms ):

• A need to urinate often day and night (frequent urination)
• An urgent need to urinate (urgent urination)
• Difficulty starting or stopping urinating
• A weak or slow urine stream
• A stream of urine that stops
• A feeling of not emptying your bladder
• Difficulty controlling your bladder (urine leakage)
• Pain or burning sensation when urinating
• Difficult or painful ejaculation
• Presence of blood in urine or semen (rare)

Signs and symptoms of advanced cancer

Signs and symptoms when it spreads outside the prostate

Cancer that started in the prostate then spreads to the pelvic nodes (these are not the same nodes as those in the groin, which are noticeable: the pelvic nodes are found deep in the belly, near the prostate; do not see them and we do not feel them). This is called lymph node metastasis. These lymph node metastases do not cause pain, but can occasionally cause edema (swelling) of the feet and ankles (see why below).

In the even more advanced stage of the disease, cancer cells have usually migrated to the bones, especially those of the pelvis and spine (these are bone metastases).

If the metastases are large enough, then the following symptoms may appear:

• Pain in the lower back or hips
• Numbness or paralysis of the lower extremities (in the spine, metastases can compress the spinal cord)
• Edema (swelling) of the feet and ankles (lymph node metastases can cause poor lymphatic drainage in the lower limbs)
• Weight loss and impairment of general condition (we do not feel well)
• Constant fatigue and pallor (bone metastases can cause anemia)

To contact our experts please call or write to us on the following number, tel / WhatsApp
: +229 51374202

GRAND MOTHER'S PROSTATITIS

Prostate cancer occurs in the later stages of inflammation of the prostate, a common result after untreated prostatitis. Men who ignore prostatitis are actually risking their lives. If you want to live long and be healthy, if you need an erection and a normal libido, you must treat the inflammation of the prostate. And it should be done as soon as possible. Here is the natural treatment from the experts at Dawasanté to cure prostatitis permanently. Click on the image below to discover this natural treatment. 

It should be understood that prostatitis is a fatal disease that can escalate and lead to a cancerous tumor. The untreated and misdiagnosed disease develops rapidly and can lead to cancer in just 1 to 2 years and often leads to the death of the sufferer

The bad news is that in 96.7% of cases, men who suffer from prostatitis suffer from sexual weakness sooner or later. 

Now let's look specifically at the most effective natural treatments for treating prostatitis and for prostate health in general.

Natural remedies, easy to find and use, effective not only because they reduce inflammation, but also because they are able to "  deflate the prostate  ", thus countering the problem of benign prostatic hypertrophy. , significantly improving urine flow and thus facilitating urination.

Some of these remedies are therefore also useful for the strong antibacterial and immunostimulating properties, which are very useful in cases of prostatitis of bacterial origin.

These remedies can be taken alone or all together.

If you are already taking medication for prostatitis (or other illnesses), before taking any of these herbs, or any supplement, I strongly advise you to consult your doctor.

To remedy this we offer you some solution related to certain plants and your food

1 - aloe juice

Aloe, from a phytotherapeutic point of view, is without a doubt one of the most complete and effective natural remedies, so much so that it can be used to treat and prevent an endless number of diseases. Prostatitis is no exception.

Due to its rich assets  (vitamins, minerals, flavonoids, amino acids, anthraquinones, polysaccharides, etc.), Aloe has antimoral, immunostimulatory, anti-inflammatory, antibacterial, antifungal and antiviral properties.

Oral consumption of aloe juice helps reduce inflammation of the prostate and bladder, shrinks the size of the prostate, and effectively neutralizes bacterial infections.

There are several varieties of Aloe, the one with the most active ingredients is definitely  Aloe Arborescent  (not Aloe Vera!).

This plant uses leaves which, after removing the thorns, must be mixed with honey and a little grappa (or other distillate). The result is a greenish and frothy juice, slightly bitter and rich in healthy properties.

2 – Epilobium

Epilobium is the quintessential prostate herb, as it has been used for over a century in traditional medicine to specifically treat all diseases that affect this gland, such as prostatitis and prostatic hyperplasia. Indeed, soon after its consumption, the effects already begin to be felt, with greater ease to urinate and completely empty the bladder. Indeed, Epilobium exerts a rapid and effective anti-inflammatory action against the bladder and the prostate, while reducing the size of the prostate.

3 - Bee pollen

Bee pollen is a treasure trove of nutritious and healthy substances.

In fact, it contains 35% protein, 21 amino acids of 23, 35% carbohydrate, 5% fat (mostly unsaturated aids), all vitamins (except vitamins B4 and F), minerals and flavonoids. In fact, several studies confirm that consuming bee pollen is effective in fighting prostatitis and enlarged prostate, as it reduces pain and inflammation and inhibits the proliferation of prostate tissue.

4 - Root and nettle leaves

Nettle (Utica dioica) is another natural remedy commonly used in the treatment of prostatitis.

A  study was recently published in 100 patients with benign prostatic hyperplasia, where the effects of nettle on reducing the size of the prostate are confirmed. The leaves of root and nettle are used to treat prostate problems. With the leaves, you prepare an herbal tea (simply let the leaves infuse for 10 minutes in hot water then filter). The root is used as a decoction instead. Nettle root is sometimes used in conjunction with saw palmetto. To further determine its effectiveness

5 - Pumpkin seeds

Pumpkin seeds have a long tradition in traditional medicine, in the treatment of intestinal worms as well as in the treatment of prostate disorders.

This is thanks to the very high zinc content.

In fact, zinc affects androgen metabolism by inhibiting the activity of the enzyme that converts testosterone to DHT, 5alpha-reductase. It is an androgenic hormone that is fundamental for the development and normal growth of the prostate. Nevertheless, it is also recognized that it is the cause of hyperplastic nodules of the gland, which can eventually lead to benign prostatic hyperplasia (BPH).

In addition, zinc reduces the secretion of prolactin, a hormone that activates a testosterone booster in the prostate. The higher the testosterone, the higher the production of DHT. By reducing the synthesis of prolactin, zinc also ensures lower DHT.

The seeds of pumpkin contain beta-sitosterol, a compound similar to cholesterol and present in some plants. Preliminary studies have shown that beta-sitosterol can improve urine flow and reduce the amount of urine left in the bladder after urination.

Some studies recommend taking 10 g of pumpkin seed extract per day for symptoms of BPH.

6. Pygeum (African plum extract)

Pygeum has also been shown to contain a wide range of fatty acids, alcohols and sterols, such as beta-sitosterol, which have an antioxidant and anti-inflammatory effect on the urogenital tract.

A few studies indicate that consuming 100 to 200 mg of Pygeum extract daily or splitting it into two doses of 50 mg twice daily may help reduce symptoms of BPH.

7. Saw Palmetto

Saw palmetto is one of the most studied and widely used herbal supplements to treat BPH.

Several studies have linked saw palmetto to reduced symptoms of BPH. This is probably due to the fact that it inhibits the production of testosterone and reduces the size of the inner wall of the prostate.

However, other studies have not been able to establish whether the use of a saw palmetto supplement has an impact on BPH symptoms compared to a  placebo.

8. Zi-Shen Pill (ZSP)

The Zi-Shen (ZSP) pill contains a blend of three herbs, including   Chinese cinnamon.

The formula comes from ancient Chinese medicine dating back to the 13th century. Trusted Source researchers showed that rats given the Zi-Shen formula exhibited reduced levels of BPH.

More research is needed in humans to determine its effectiveness.

9. Cernilton

Some people use herbal supplements made from rye pollen to treat symptoms of BPH. These bothersome symptoms may include the inability to empty the bladder completely and the need to urinate frequently at night.

Under the Cernilton brand, rye pollen is included in the formulation of several registered pharmaceutical supplements intended to alleviate the symptoms of BPH.

Despite its popularity, it has never been shown  Cernilton had an impact on symptoms of BPH as part of scientific studies on a large scale. However, some indicate that it can help reduce the overall size of the prostate.

More research is needed to determine if it works or not.

10. Orbignya speciosa (babassu)

Babassu or  Orbignya speciosa is a species of palm native to Brazil. Several indigenous Brazilian tribes and communities use the dried or ground kernels from the tree to treat urogenital symptoms and conditions.

Babassu nut oil has also been shown to be a source for inhibiting testosterone production, while other parts of the nut contain compounds with anti-inflammatory and antioxidant properties.

11. lycopene

Lycopene is a natural pigment found in many fruits and vegetables. One study has shown that it may help slow the progression of BPH.

Tomatoes are the richest source of lycopene available to most people. But a few other fruits and vegetables contain lower levels of this antioxidant.

Usually, the more pink or red the fruit or vegetable, the higher its lycopene content.

Other sources of lycopene include:

• Papaya
• pink grapefruit
• watermelon
• goyave
• carrots
• Red peppers
• apricots
• Red cabbage

12. Zinc

l  has been shown that chronic zinc deficiency potentially increasing the likelihood of developing BPH. Taking zinc supplements or increasing dietary zinc intake can help reduce urinary symptoms associated with an enlarged prostate.

Zinc is found in poultry, seafood, and several types of seeds and nuts, such as sesame and pumpkin.

13. green tea

Green tea contains many antioxidants called catechins,  which strengthens the immune system and possibly slow the progression of cancer the prostate.

It is important to keep in mind that green tea contains caffeine. Caffeine can stimulate the bladder and cause a sudden urge to urinate which can worsen the symptoms of BPH.

PROSTATIC HYPERTROPHY

An enlarged prostate is a common condition in men. An enlarged prostate can cause unpleasant urinary symptoms, such as blocking the flow of urine out of the bladder. It can also cause bladder, urinary tract, or kidney problems.

There are several effective treatments for prostate enlargement, including medications, minimally invasive therapies, and surgery. To choose the best option, you and your doctor will consider your symptoms, the size of your prostate, other health concerns, and your preferences. Visit the natural herbal treatment of Dawasanté experts to definitively cure the enlarged prostate. Click on the image below to discover this natural treatment.

We deliver all over the world.

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

    Treatment

If you suffer from an enlarged prostate, here is the miracle solution that will allow you to naturally cure or prevent your enlarged prostate. The natural remedy to permanently and quickly cure the enlarged prostate that we offer is composed of two elements: an herbal tea and an ointment. Generally, with the exception of the diagnosis too late, our natural treatment makes it possible to cure the enlarged prostate quite easily and does not leave any sequelae. So trust us! This natural treatment is the secret to treating an enlarged prostate without operation, without side effects thanks to plants.

Herbal tea is made from plants that have anti-inflammatory, astringent, antibacterial and calming properties. It works in particular by reducing the swelling of the prostate gland and providing immense relief. This natural remedy also contains several natural anti-inflammatory compounds that inhibit the inflammatory process that triggers inflammation and pain in the prostate gland. It also helps relieve urinary symptoms, including those caused by an overly large prostate without having to have an operation. The natural remedy also helps in curing difficulty in urinating and it restores sexual balance. It is therefore the secret to cure hypertrophy of the prostate with plants.

First, the pain in your lower back and in your penis will gradually disappear. You will no longer have difficulty urinating and your erection will gradually return to normal. The use of herbal products to treat an enlarged prostate gives excellent results. Our therapy to cure the enlarged prostate that we offer is effective, fast, long-lasting. So; it will save you from having to go through an operation. Herbal tea to treat an enlarged prostate has no side effects, either on the body or on health. Our natural treatment is secure. So this is the secret to cure enlarged prostate without surgery and without side effects.

To discover our natural remedy to cure an enlarged prostate, click here

    Symptoms

The severity of symptoms in people with an enlarged prostate varies, but symptoms tend to gradually worsen over time. Common signs and symptoms of an enlarged prostate include:

Frequent or urgent need to urinate

Increased frequency of nighttime urination ( nocturia )

Difficulty starting to  urinate

Weak urine flow or flow that stops and starts

Dribble at the end of urination

Inability to completely empty the bladder

Less common signs and symptoms include:

 Urinary tract         infection

Inability to urinate

Blood in the urine

The size of your prostate doesn't necessarily determine the severity of your symptoms. Some men whose prostate is only slightly dilated may have severe symptoms, while others in those with a severely enlarged prostate may only have minor urinary symptoms.

In some men, symptoms eventually stabilize and may even improve over time.

    The causes

The prostate is located below the bladder. The tube that carries urine from the bladder out of your penis ( urethra ) goes through the center of the prostate. When the prostate gets bigger, it begins to block the flow of urine.

Most men have continued to grow prostate in their lifetime. In many men, this continued growth enlarges the prostate enough to cause urinary symptoms or significantly block urine flow.

The cause of prostate enlargement is not entirely clear. However, it could be due to changes in the balance of sex hormones as men get older.

    Risk factors

Risk factors for prostate enlargement include:

·          Aging. An enlarged prostate rarely causes signs and symptoms in men under the age of 40. About a third of men have moderate to severe symptoms by age 60 and about half by age 80.

·          Family history. Having a blood relative, like a father or sibling, with prostate issues means you're more likely to have issues.

·          Diabetes and heart disease. Studies show that diabetes, along with heart disease and the use of beta-blockers, may increase the risk of an enlarged prostate.

·          Way of life. Obesity increases the risk of an enlarged prostate, while exercise can lower your risk.

    Complications

Complications of an enlarged prostate can include:

·          Sudden inability to urinate (urinary retention). You may need to insert a tube (catheter) into your bladder to drain urine. Some men with enlarged prostate need surgery to relieve urinary retention.

·          Urinary tract infections (UTI). The inability to completely empty the bladder can increase the risk of urinary tract infection. If UTIs occur frequently, you may need to have surgery to remove part of the prostate.

·          Bladder stones. These are usually caused by an inability to completely empty the bladder. Bladder stones can cause infection, irritation of the bladder, blood in the urine and obstruction of its flow.

·          Damage to the bladder. A bladder that has not completely emptied can stretch and weaken over time. As a result, the muscle wall of the bladder no longer contracts properly, making it more difficult for your bladder to empty completely.

-          Renal lesions. The pressure of urinary retention in the bladder can directly damage the kidneys or allow bladder infections to reach the kidneys.

Most men with an enlarged prostate do not develop these complications. However, acute urinary retention and kidney damage can pose serious health threats.

Having an enlarged prostate is not thought to increase the risk of prostate cancer.

    Diagnostic

Your doctor will start by asking you detailed questions about your symptoms and giving you a physical exam. This initial examination is likely to include:

·          Digital rectal examination. The doctor inserts a finger into your rectum to check your prostate for enlargement.

·          Test of urine. Testing a sample of your urine can help rule out infection or other conditions that can cause similar symptoms.

·          Blood test. The results may indicate kidney problems.

·          Blood test with prostate-specific antigen (PSA). PSA is a substance produced in your prostate. PSA levels increase when the prostate is enlarged. However, high levels of PSA can also be due to recent procedures, infection, surgery, or prostate cancer.

Transrectal ultrasound. An ultrasound probe is inserted into your rectum to measure and assess your prostate.

·          Prostate biopsy. Transrectal ultrasound guides the needles used to take tissue samples (biopsies) from the prostate. Examining the tissue can help your doctor diagnose or rule out prostate cancer.

·          Urodynamic and pressure-flow studies. A catheter is inserted into your bladder through your urethra. Water - or, less frequently, air - is slowly injected into your bladder. Your doctor can then measure the bladder pressure and determine how your bladder muscles are working. These studies are typically only used in men with suspected neurological problems and in men who have had a previous prostate procedure and still have symptoms.

·          Cystoscopy  A flexible, lighted instrument (cystoscope) is inserted into your urethra, allowing your doctor to see inside your urethra and bladder. You will be given a local anesthetic before this test.

    Medical treatment

A wide variety of treatments are available for an enlarged prostate, including medications, minimally invasive therapies, and surgery. The best choice of treatment depends on several factors, including:

The size of your prostate

· Your age

Your overall health

The amount of discomfort or discomfort you feel

If your symptoms are tolerable, you may decide to defer treatment and just watch your symptoms. For some men, symptoms may improve without treatment.

We deliver all over the world.

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

PROSTATITIS FOODS

Prostate degeneration: a scourge for men

The cancer prostate is the most common cancer in men in Western countries. Each year, more than 40,000 cases are diagnosed in France. In addition, numerous studies carried out since the seventies lead to think that food is involved for 30 to 40% in the genesis of cancers in general. At the same time, and still in France, 70,000 men each year undergo an operation linked to benign prostatic hypertrophy.

Knowing that a number of dietary factors are involved in degenerative prostate disease, it is important for men to be vigilant about the contents of their plate. However, Dawasanté experts provide you with a natural herbal treatment to cure prostatitis. 

NATURAL TREATMENT FOR PROSTATITIS

This natural treatment to permanently and quickly cure prostatitis that we offer is composed of two elements: a herbal tea and an ointment. It also helps relieve urinary symptoms, including those caused by an enlarged prostate without having to have an operation. It works in particular by reducing the swelling of the prostate gland and providing immense relief. The natural treatment also helps cure urination difficulties and it restores sexual balance. So this is the secret to cure prostatitis by plants without surgery and without side effects.

CLICK HERE TO GET THIS PRODUCT!!

To contact our experts please call or write to us on the following number, tel / WhatsApp
: 0022996374527

WE DELIVER ALL OVER THE WORLD

The current literature abounds in articles on the relationship between certain foods and the occurrence of prostate cancer. Even more in the field of nutrition than in others, separating the chaff from the wheat is not easy. Knowing this, and although we can not confirm anything in the face of data which are still mostly at the research stage, it seemed useful to us to carefully list the foods most often incriminated today in degenerative disease. prostate.

Gentlemen, take care of your prostate

From 10 to 20% of prostate cancers could be prevented with a balanced diet. Extenso reviews with you the content of your plate ...

Foods to choose

Vegetables, more vegetables!

It's an indisputable fact: vegetables play a major role in cancer prevention. To enjoy their benefits, fill half your plate with vegetables. Vary the colors to take advantage of the different compounds they offer.

Also, although they are not all particularly colorful, vegetables belonging to the cruciferous family, such as cauliflower, broccoli, bok choy and Brussels sprouts also have anti-cancer properties. Consuming it at least 5 times a week could decrease the risk of developing prostate cancer.

Vitamin E and selenium

Selenium, which is found in rice, wheat, and Brazil nuts, would provide a protective effect. However, its effect would be seen especially in men who have low amounts of selenium in their blood.

Vitamin E, found in almonds, flax seeds, hazelnuts, safflower, corn and soybean oil would also be beneficial in prevention. Its role would be particularly effective in smokers and in those who have low amounts of vitamin E in the blood.

 Broccoli, and more broadly vegetables from the cruciferous family, help prevent the onset of certain cancers including prostate cancer.

​

The broccoli isothiocyanates including sulforaphane, and ibérine that appear to act on the expression of genes (6). According to some authors, when a person develops cancer, certain genes are activated and others repressed in particular, and other crucifers such as Brussels sprouts contain; However, broccoli seems to stimulate genes that prevent cancer and slow down genes that facilitate its growth, by chemical modification of ligands.

- It is recommended to drink green tea daily. Its benefits are manifold. It contains catechins, an antioxidant substance that is said to help limit the development of tumors. 

Other foods contain less lycopene:  pink grapefruit,  watermelon,  papaya,  guava,  dried apricots, for example.

- The pomegranate. "It is less known but pomegranate juice is a real ally for the health of his prostate. You can drink a glass every day," says Professor Zerbib. The antioxidants present in the pomegranate fruit are said to be responsible for these benefits. 

- Curcumin.  Several studies have shown that curcumin has anti-tumor effects. "Consumption once or twice a week is sufficient," advises Professor Zerbib.

Regarding alcohol, it is better to be careful of white alcohols such as white wine, champagne and beer which promote urinary disorders and infections but have no direct effect on tumor growth.

The best prevention is early detection of prostate cancer for men who have risk factors, including family history. 

Lycopene

Lycopene is a substance from the carotenoid family. It is a powerful antioxidant. The tomatoes are rich in lycopene. This lycopene is better assimilated in cooked tomatoes (tomato sauces, coulis, purées) than in raw tomatoes, except tomato juice which also offers good availability of lycopene.

But don't we say that cooking deteriorates certain food components, such as vitamins for example?

Certainly yes. Nevertheless, cooking seems rather beneficial to the antioxidant score, at least concerning the tomato.

Thus, its vitamin C content effectively decreases by cooking, but its concentration of phenols increases, so that the water-soluble anti-radical capacity increases.

Without being specific to prostate cancer, let us also point out a meta-analysis published in the Journal of the National Cancer Institute on 2/17/99, which shows that men consuming more than 10 times a week of tomato products have a 33 % lower risk of developing cancer compared to those who consume less than twice a week.

It is interesting to consume lycopene almost daily, in the form of vegetables and fruits.

Isothiocyanates

Polyphenols

Polyphenols are what give food color.

The polyphenols in tea would protect against prostate cancer, and in particular green tea, the daily consumption of which could reduce the occurrence of prostate cancer by around two thirds.

Certain authors nevertheless emphasize the fact of consuming preferably teas resulting from a culture free from phytosanitary products such as pesticides or heavy metals. It also seems logical to extrapolate this remark to all of our nutrients.

A recent study conducted by NutriNet-Santé cites coffee as a major source of beneficial polyphenols among the French.

The red wine is rich in Resveratrol is a polyphenol. The rougher the wine, the more resveratrol it contains. This substance is antioxidant, anti-inflammatory, and would have an estrogenic effect (inhibiting testosterone, a male hormone which has a proliferative action on the prostate). 4 glasses of red wine per week would slow the progression of the disease by 41%

Consuming 250 ml of pomegranate juice every day would reduce the occurrence of prostate cancer by 60%.

The fruits and vegetables are rich in polyphenols cancer-protective, but not specific for prostate cancer. It is from this observation, among other things, that the National Health Nutrition Plan recommended 5 fruits and vegetables per day.

A diet rich in soy would reduce PSA levels by 14%.

Soy contains polyphenols (genistein, family of isoflavones) which have an antioxidant and estrogenic role. Tofu, soy drinks and yogurts are rich in it. Although it is not a phenol, it is interesting to know that soybeans contain saponins, which are anti-inflammatory but above all anti-proliferation of tumor cells. Remember, however, as said above that the consumption of soy can have drawbacks (drop-in sperm, among others).

Omega 3

Omega 3s have an anti-inflammatory role. They also control testosterone. They are present in fatty fish, which by the way, also contain more vitamin D, which is also beneficial for the prostate, the more fatty they are.

The flaxseed oil, rich in omega 3 is currently under study. Flaxseed oil also contains lignans which give rise to phytoestrogens.

A study presented in June 2007 in Chicago on the occasion of the 43rd annual meeting of the American Society of Clinical Oncology showed a decrease in the proliferation of prostate cancer cells by 30 to 40% in men undergoing prostate removal in due to cancer and having previously consumed flax seeds.

The rapeseed oil has been the subject of controversy especially following an epidemiological study conducted at Harvard on a group of 50,000 physicians health professionals. According to this study, participants who consumed the most omega 3 had a higher risk of prostate cancer than those who consumed little!

While other studies say the opposite. For example, a large American prospective study conducted by the NIH (equivalent to Inserm) was published in August 2006. It involved 30,000 volunteers. She didn't find that men who consumed the most ALA (alpha-linolenic acid, omega 3) had more cancer.

Also contain omega 3:  rapeseed, walnut, wheat germ oils.

Monounsaturated fatty acids

These good fats would be favorable to prostate tissue. It is about olive oil , peanuts, hazelnuts but also  almonds  and  avocados  as well as goose fat, duck.

Vitamin D

Men with above-average plasma vitamin D levels have a 45% lower risk of developing aggressive prostate cancer, according to a study by the American Society of Clinical Oncology. As a reminder, 90% of vitamin D is synthesized in our skin following sun exposure, the remaining 10% being found in our  food of animal origin  (eggs, non-skimmed dairy products,  fatty fish, etc.).

On the other hand, we will see later that one should not abuse too fatty products.

Selenium

Selenium is a powerful antioxidant. 200 micrograms of selenium reduce the incidence of prostate cancer by 63%. But 400 micrograms of selenium have a reverse action by pro-oxidant effect!

The  Brazil nut  contains a lot of selenium. The garlic  and  broccoli  are also well provided. The  red onions  also contain enough. Onion is a very interesting food against the occurrence of prostate cancer and other cancers, in particular by its content of phenols and flavonoids.

Lutein

Lutein is a carotenoid with antioxidant properties and capable of promoting apoptosis (programmed cell death, 100 times more common for tumor cells than for healthy cells).

The lawyer  is particularly well endowed with it. It is in any case a food to recommend. An acetone extract of avocado inhibits the in vitro growth of both androgen-dependent and androgen-independent prostate cancer cells.

Consuming 50 grams of avocado per day would reduce prostate cancer mortality by 40%.

Other hypothetical protectors

Pumpkin seed oil  is also sometimes cited still for its antioxidant action. It can be used mixed with other edible oils to season dishes.

Dietary factors that attack the prostate

The alcohol

The alcohol  should be consumed in moderation. Alcohol seems to be involved in many cancers (16).

Fats

Industrialized products containing  hydrogenated lipids should be  consumed in moderation.

Products containing  saturated and trans fatty acids should  also be consumed in moderation.

Among the foods containing trans fatty acids, we can mention  margarines ,  cookies ,  pastries ,  fried foods .

The  red meats  and  cold cuts  are often stigmatized by their intake of saturated fatty acids. However, red meats are not necessarily very high in fat. However, according to a study conducted in 2000, it still takes a daily fat consumption corresponding to more than 33% of the calories of the day to multiply by 3 the risk of prostate cancer.

While it is true that omega 3s are considered favorable to the prostate, it is accepted that  omega 6s  ( corn oil , walnuts, grape seed, sunflower, etc.) generally attack this prostate tissue.

It should be noted that obesity  must be fought here as in the fight against other cancers: the risk of death from prostate cancer is doubled with a body mass index exceeding 30. The prostate is larger on average by 32% in the obese. In the same vein, and to fight cancer in general, you must avoid a sedentary lifestyle. A low calorie diet and moderate physical activity (30 minutes of walking per day) would reduce mortality by 10 to 30%. Be careful, however, not to overdo it: more than 2 hours a day has a pro oxidizing effect

Food supplements

According to some authors, the excess intake of antioxidants  eliminates too many free radicals.

Free radicals are certainly responsible for the occurrence of cancer, but their presence is also useful in the elimination of cancer cells which are rich in them and which can be self-destroyed by this auto-intoxication. According to these authors, it is therefore necessary to avoid industrial antioxidant supplements, to stick to a good diet sufficiently supplying natural antioxidants. So be careful with "food supplements".

Preparation methods

The acrylamide  promotes the onset of prostate cancer. This substance is found in  crisps  and   breakfast cereals . This is linked to the cooking method.

The  polyamines  found in  cold cuts  in the form of  nitrosamines  during salting and smoking seem to promote prostate cancer.

In particular, it is known that polyamines increase PSA and bone pain from prostate metastases.

Overcooking, leading to the presence of  polycyclic aromatic substances  can be carcinogenic. Example with the blackening of overcooked meats.

Beware of excess!

It is likely that selenium and vitamin E taken in too much can have harmful effects on your health. It is therefore preferable to include foods that contain them in your diet rather than consuming them in the form of supplements. In fact, supplements have not been shown to help prevent prostate cancer.

Foods to eat in moderation

Fatty substances

A diet high in fat, especially animal fat, would increase the risk of developing prostate cancer. In addition, excess fat in the diet could lead to excess weight. Since excessive calorie consumption and obesity are two factors linked to a greater risk of prostate cancer, it is best to ensure that you meet your energy needs, without exceeding them.

Tips to limit harmful fats:

· Prefer cooking with steam, in the oven or on the grill rather than deep frying;

· Reduce your consumption of pastries and baked goods (croissants, commercial muffins, donuts, etc.).

· Decrease your consumption of animal fat, by varying your sources of protein: include fish and legumes more often in your menu;

· Favor non-hydrogenated oils and margarine over animal fats;

· Choose leaner cuts of meat;

· Switch to low fat milk and alternatives.

Red meat and cold cuts

Red meats, mainly those that are grilled, could promote the appearance of certain cancers, including that of the prostate. Processed meats (ham, bacon, cold meats and cold cuts) could also play a harmful role.

At lunchtime, choose canned fish, chickpea or tofu spreads and leftover roasts rather than the traditional slices of ham, salami or "baloney".

Calcium and dairy products

Although calcium is an absolutely essential nutrient for the development and maintenance of bone health, it seems that excessive consumption may be linked to a greater risk of developing prostate cancer. To enjoy the benefits of calcium without risking the disadvantages as well, it is recommended that you do not take calcium supplements that provide more than 1000 mg.

High consumption of whole, partially skimmed, or fat-free dairy products has been linked to an increased risk of developing prostate cancer. This link is not clear and more studies still need to be done. 

Canada's Food Guide classifies dairy products as a protein food. They therefore have their place in your diet, without having to give them a disproportionate importance. 

To contact our experts please call or write to us on the following number, tel / WhatsApp
: 0022996374527

WE DELIVER ALL OVER THE WORLD

DEFINITION

The prostatitis is an inflammation caused by a bacterial infection of the prostate.

This organ is an endocrine gland in the male genital system which has the function of producing the seminal fluid necessary for the development and mobility of sperm.

Conventional care for prostatitis requires the use of a cytobacteriological examination of the urine to identify the pathogen responsible for the disease.
As for herbal treatments, they help relieve the painful symptoms of prostatitis and speed up healing.  Here is the natural treatment from the experts at Dawasanté herbal medicine to cure prostatitis. Click on the image below to discover this natural treatment.

We deliver all over the world.

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

In this context, an effective mutual or insurance allows benefiting from high reimbursements of the expenses of consultations of urologists, ultrasounds and biological analyzes as well as herbal remedies prescribed by the doctors.

PLANTS TO RELIEVE PROSTATITIS

Saw palmetto to relieve benign prostatic hyperplasia

The saw palmetto  (Serenoa repens)  is a shrub whose berries contain sterols, substances which have the property of relieving the symptoms of BPH. Several cross-analyzes of clinical trials of good methodological quality have confirmed the interest of saw palmetto extracts in the treatment of BPH.

Commission E and WHO recognize the use of saw palmetto in "the treatment of urinary difficulties associated with BPH".

The EMA grants the status of “well-established medical use in the symptomatic treatment of BPH” only to saw palmetto extracts obtained with hexane as an extraction solvent. In addition, it only grants the status of "traditional use to relieve symptoms of the lower urinary tract associated with BPH" to saw palmetto extracts obtained with ethanol as an extraction solvent.

In France, drugs based on saw palmetto extracts are available for this use, only one of which uses hexane to extract the active ingredients and none uses ethanol.

African plum to relieve benign prostatic hyperplasia

The  African plum  (Pygeum africanum)  is a tree whose bark is used to produce standardized extracts containing sterols and docosanol. A cross-analysis of eighteen clinical trials points to some efficacy of African plum extracts in the treatment of BPH, but less than that of saw palmetto extracts.

The EMA grants “traditional use to relieve symptoms of the lower urinary tract associated with BPH” status only to African plum extracts obtained with chloroform as an extraction solvent.

In France, drugs based on saw palmetto extracts are available for this use, none of which uses chloroform for the extraction of the active ingredients.

Pumpkin seeds to relieve benign prostatic hyperplasia

Pumpkin seed extracts  (Cucurbita pepo)  are recognized by Commission E to “facilitate the emission of urine in men suffering from BPH”. These seeds contain many substances (phytosterols, essential fatty acids, etc.) whose action on the prostate is poorly understood. There are few studies of pumpkin seeds used on their own (they are often combined with other herbs offered in the treatment of BPH). Their use in this indication is based on tradition.

The  root of stinging nettle  to relieve prostate benign

The roots of stinging nettle  (Urtica dioica)  contain lignans, with properties similar to those of female hormones and which could explain their effects on the prostate. However, clinical trials evaluating the effects of nettle root on prostate adenoma are of poor methodological quality. They point to the effectiveness of nettle root without providing scientific proof.

Unlike other official sources (WHO, Commission E and ESCOP), the European Medicines Agency (EMA) considers that these studies are inconclusive and that BPH being a disease that must be treated medically, the root nettle can not be considered a traditional treatment for this pathology.

Against prostate cancer: coffee and tomatoes

No plant to date can accompany or cure prostate cancer. On the other hand, in prevention, a large study carried out on 48,000 people by the National Cancer Institute was able to establish that consumption of 6 cups of coffee per day reduced the risk of 60% of suffering from cancer of the prostate. Unfortunately, consuming so much coffee daily is not reasonable: in addition to a phenomenon of dependence, excess caffeine causes many side effects, such as nervousness, restlessness, anxiety, palpitations, insomnia, stomach irritation. , diarrhea ...

The good news, decaffeinated offers the same virtues. It is indeed the polyphenols in coffee, and not caffeine, which gives it these preventive properties. A similar study published by the same institute also showed that consuming cooked tomatoes two to three times a week reduces the risk of developing prostate cancer by a third (compared to occasional consumption). Finally, healthy living remains effective prevention: avoiding exposure to toxic products, including pesticides (farmworkers are more exposed to this cancer), being active and limiting the consumption of red meat, cold meats and cheeses. fatty, while favoring large rations of fruits, vegetables and fish.

Treatment of prostatitis: treatment of inflammation and contributions of phytotherapy in case of prostatic hypertrophy

Prostatitis requires drug therapy with antibiotics and anti-inflammatories. This cure lasts from 3 to 8 weeks depending on the germ causing the infection.

Besides antibiotic therapy, the patient may resort to herbal remedies to relieve the symptoms of an enlarged prostate such as:

• bearberry: anti-inflammatory and soothing pain in urination, this plant is prescribed in cases of acute prostatitis and cystitis. Also called bear grape, it is an antiseptic and powerful antibacterial against pathogenic bacteria of the urinary tract.
• giant sequoia: antidepressant and hormonal regulator, giant sequoia buds help to treat inflammation in cases of prostatic hypertrophy. They are also effective in stimulating appetite and reducing the fatigue that accompanies prostatitis.
• pumpkin seeds: they are used in herbal tea against urinary disorders associated with an enlarged prostate. These seeds are also effective in relieving pain, facilitating mixing, etc.
• serenoa repens: the berries of this saw palmetto are used to treat inflammation of the prostate and prevent a recurrence

Massages of the genitourinary area of ​​the prostate with essential oils (Scots pine, cypress, peppermint, etc.) are also recommended to relieve symptoms and prevent prostatitis.

Oral antibiotic intake and herbal medicine find their limits in severe prostatitis. Hospitalization for 2 to 4 days is then required in order to put the patient on intravenous antibiotic therapy.

Prostatitis: symptoms, types and risk factors of prostatic hypertrophy

Prostatitis causes enlargement of the gland and compression of the urethra and bladder. The first clinical signs of this prostatic hypertrophy are pain and discomfort when urinating, which results in the accumulation of urine residues at the origin of the aggravation and complication of the urological disease.

Inflammation of the prostate can be either:

• acute prostatitis: usually of bacterial origin, it is characterized by high fever, severe pain in the lower abdomen and general fatigue. The patient also experiences frequent urges to urinate despite the small amounts of urination expelled
• chronic prostatitis: of bacterial or non-bacterial origin, it is the consequence of a poorly healed urinary tract infection. This recurring pathology manifests itself by twitching in the lower abdomen, aggravated by retention of urine

The enlarged prostate is favored by:

• the stress
• sexually transmitted infections
• urogenital malformation
• prolonged sitting (office, car, plane)
• the practice of certain sports such as horse riding or cycling

Prostatitis affects young men. It is often associated with psychological impacts and a deterioration in the quality of life due to painful symptoms, incontinence and difficulty in sexual relations.

We deliver all over the world.

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

T ERATOSPERMY FOOD: Bark, Roots, Herbal teas, Plants 

The teratozoospermia  (or teratozoospermia) is a sperm abnormality characterized by sperm having morphologies defects. Due to these deformities, the fertilizing power of sperm is impaired, and the couple may have difficulty conceiving.

However, Dawasanté experts provide you with a natural treatment to permanently cure teratospermia.

Click HERE or on the image below to discover this treatment

We deliver all over the world.

For more information, you can contact our experts at +229 51374202 direct line or by WhatsApp at the same number

If we readily recognize that food has an influence on the fertility and the state of health of the future baby, strangely, we always have in mind the hygiene of the mother's life. Often ignoring the role of men. Yet recent studies have shown that certain micronutrients improve sperm quality. In couples wishing to have a child, which foods should be favored for him? The answers of Doctor Laurence Benedetti, specialists in micronutrition.

“Today, even among young people, there are more abnormalities in the spermogram. Stress, the cell phone in your pocket, pesticides and pollutants undoubtedly play a role, ”notes Dr. Laurence Benedetti. Food can help counter the negative effects of the environment. A diet to start when you want a child to give the future dad time to replenish his stock of antioxidants and good nutrients.

The nutrients men need

- Antioxidants (vitamin C, A, E, polyphenols).  Insofar as they play a role of shield against external aggressions (stress, tobacco, pollution), they also protect the integrity of the spermatozoa.
On the plate: Green vegetables, fruits, spices (turmeric, ginger, curry…), green tea, dark chocolate.

-  Omega 3 .  As they act on the flexibility of the cell membrane, they facilitate exchanges between the oocyte and the spermatozoon.
On the plate: Small fatty fish (sardines, herrings, mackerel), rapeseed oil, walnut oil

- Magnesium.  Known for its anti-stress effects, it is recommended in the pre-conceptual period. Stress harms libido and is also believed to be implicated in fertility problems.
On the plate: Cereals and legumes (lentils, white beans, split peas), which provide magnesium and other minerals (iron, calcium, potassium, etc.)

- Vitamin B9.  Studies have shown that there is a correlation between infertility and low intake of vitamin B9.
On the plate: Green leafy vegetables (lamb's lettuce, salad, broccoli), brewer's yeast or liver.

- Zinc.  As a bulwark against oxidative stress, studies have shown that it is present in high concentration in seminal fluid.
On the plate: Oysters, wheat germ.

- Selenium. it plays a role in the maturation of sperm, according to some studies.
On the plate: Seafood

- Carnitine and coenzyme Q10.  This amino acid derivative and this antioxidant, which ensure the production of energy within the cell, are very useful for the spermatozoon, which consumes a lot of energy.
On the plate: Proteins (meat, fish).

On the side of plants

Tribulus and mucuna are known to improve the spermogram. They can be combined in the form of standardized plant extracts (ask a pharmacist specializing in herbal medicine) or in the form of capsules.

On the side of food supplements
 

Androbiane , Pileje laboratories. It contains L-Carnitine, N-acetyl-L-carnitine, magnesium, coenzyme Q10, zinc, vitamins, selenium. One sachet per day in the preconception period, two sachets per day in the event of a slightly weak spermogram.
 

Conceptio Homme , Granions laboratories. Based on coenzyme Q10, vitamin E and B6, L-Carnitine, DHA, zinc and selenium, it is recommended as a 6-month program.

And also in everyday life

In addition to diet, you must of course adapt the rules of a healthy lifestyle: play sports (without excess), stop smoking, limit your alcohol consumption, sleep well, eat a balanced diet, start to distance from paints stuffed with solvents and pesticides. Finally, less known,  sperm must be kept at a temperature 2 ° C lower than the rest of the body. This means it's best to forget about saunas and hot tubs, tight clothes and do away with the habit of resting the laptop on your lap.

TERATOSPERMY FOOD: Bark, Roots, Herbal teas, Plants

We deliver all over the world.

For more information, you can contact our experts at +229 51374202 direct line or by WhatsApp at the same number

ALL ABOUT SPERMATOZOIDS: Bark, Roots, Herbal Teas, Plants

A spermatozoon is a mobile male reproductive cell (or gamete) involved in sexual reproduction. During fertilization, the sperm unites with an egg or an oocyte (female gamete) to form an egg cell, which will then develop into an embryo to give a new individual. This is how the Dawasanté experts provide you with a natural treatment to treat your problems with sperm abnormalities (oligospermia, necrospermia, asthenospermia, teratospermia, azoospermia, etc.).

Click on the image below to discover this natural treatment 

We deliver all over the world. 

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

The possible link between male infertility and chromosomal abnormalities in spermatozoa has been explored in several studies, since the advent of the technique of fluorescence in situ hybridization (FISH).

INTRODUCTION

Chromosomal abnormalities in humans may be responsible for infertility. In fact, the prevalence of abnormalities detected in the blood karyotype is ten times higher in infertile men than in the general population, ie around 5.3%, versus 0.6%. Numerical and structural abnormalities of the sex chromosomes are found with a high frequency, especially in men with severe azoospermia or oligo-astheno-teratospermia (OAT). The treatment of choice to remedy male infertility with OAT is Medically Assisted Reproduction (PMA) by  Intra Cytoplasmic Sperm Injection  (ICSI). However, it has been reported in recent years that the rate
of aneuploidy (abnormal number of chromosomes) of the sex chromosomes and de novo structural chromosomal abnormalities of paternal origin is higher in the offspring of these men. The risk of transmission of a chromosomal abnormality to offspring as the natural process of sperm selection is bypassed by the ICSI procedure should therefore be carefully considered and evaluated.

SPERMATOZOID CARYOTYPE AND FISH

Karyotypic analysis of spermatozoa makes it possible to determine in what proportion the gametes themselves are carriers of chromosomal abnormalities, in particular in infertile men.

In 1978, Rudak et al. described a technique for the karyotypic analysis of spermatozoa, based on the in vitro penetration of the latter into hamster oocytes. This technically heavy and delicate technique was only successfully practiced by a dozen laboratories around the world.

The technique of FISH (Fluorescence In Situ Hybridization) and its developments now make it possible to perform the chromosomal study of spermatozoa and analyze a large number of cells, using chromosome-specific probes that hybridize to particular regions of the DNA and can then be detected visually using a fluorescence microscope. For the FISH study, sperm from an ejaculate is spread on slides and undergo a chemical treatment resulting in the decondensation of their heads, while maintaining the structure that distinguishes them from other cells that may be in the ejaculate. Spermatozoa are also distinguished by the fact that they present signals corresponding to haploid and non-diploid cells. intact with clear hybridization signals are counted

MORPHOLOGICALLY NORMAL SPERMATOZOIDS

Morphology and motility are currently the parameters used to identify the sperm that will be microinjected as part of an ICSI procedure. Spermatozoa with an abnormal morphology are also more likely to present aneuploidy, but this risk has not been clearly quantified.

Ryu et al. studied the frequency of aneuploidy in sperm of normal morphology in infertile patients who are candidates for ICSI and all carriers of a normal blood karyotype compared to fertile patients. The morphology criterion used was that of Kruger. FISH analysis of chromosomes 18, X and Y were performed. In the group of infertile patients, and aneuploidy rate was found varying from 1.8% to 5.5% compared to 0% to 2.6% in the control patients. This result shows that the morphology of the spermatozoa is not an absolute criterion for the selection of a genetically normal spermatozoon.

Note that the different reported figures of sperm aneuploidy in men without fertility problems vary between 0 and 5% depending on the studies, differences which may be due to the use of probes with variable hybridization efficiency or to the visual interpretation of signals.

CHROMOSOMIC ANOMALIES, SPERMOGRAM AND LIFESTYLE

In a recent review, the sperm karyotypes of men without spermogram abnormalities were analyzed, with the aim of looking for possible correlations with age and lifestyle. The results of some fifty studies combining data from sperm analysis by FISH from 500 men (more than 5 million spermatozoa) were compiled. The results are an average reported rate of abnormality of 0.15% for each chromosome and 0.26% for sex chromosomes. The majority of chromosomes had an even distribution of abnormalities, with the exception of chromosomes 21, 22 and sex in which the frequencies of abnormalities were significantly higher. Trisomies 21 and 22 are also the most frequently found in the products of spontaneous miscarriages, showing the link between chromosomal abnormalities in spermatozoa and abnormalities found in the embryo. This work also demonstrated a slight increase in the frequency of disomies with paternal age, mainly for the sex chromosomes, but no effect of smoking, alcohol and caffeine consumption.

INFERTILITY AND KYOTYPES OF SPERMATOZOIDS

It is reported that 23% of men with azoospermia and 5-10% of men with OAT have an abnormal blood karyotype, resulting in a high likelihood of producing aneuploid gametes. It is known, for example, that the proportion of gametes with a chromosomal imbalance can be as high as 50% in men carrying a reciprocal translocation. However, a normal blood karyotype does not exclude the production of aneuploid gametes. An abnormal intra-testicular environment can affect spermatogenesis, in particular by disrupting the mechanisms controlling chromosome segregation during cell division.

A defect in spermatogenesis can have many origins such as systemic disease, malnutrition, endocrine disorders, obstructive pathologies and genetic defects. Indeed, a large number of severe OATs and azoospermia have genetic etiologies, including microdeletions at the level of the Y chromosome, abnormalities of meiosis, and mutations in the cystic fibrosis gene. However, “idiopathic” OAT remains the diagnosis most often retained in male infertility, despite extensive investigations to try to determine its origin. The main interest in identifying an etiology with OAT lies in the evaluation of the prognosis and the risk of producing embryos with chromosomal abnormalities.

A large study is now the source of much controversy over the relationship between spermogram abnormalities and potential risks of chromosomal abnormalities in ICSI. Fertilization and pregnancy rates obtained in relation to parameters of sperm number, mobility and morphology of infertile men were retrospectively analyzed in 966 cycles of ART with ICSI. The results showed comparable ICSI successes independent of the magnitude of OAT parameters. They concluded that in the extreme, only a living sperm in ejaculate can be sufficient for ICSI to be successful. While this study was therefore very reassuring, it does not

In order to study the etiology of “unlabelled” OATs, Calogero et al. used the FISH technique to explore the rate of aneuploidy in sperm chromosomes 8, 12, 18, X and Y in one group of patients with teratospermia, another with OAT and a control group. They observed similarly increased rates of aneuploidy in the first two groups, which suggested that teratospermia may be the critical endpoint associated with aneuploidy. The authors, therefore, recommended that a FISH analysis be performed in cases of teratospermia, before any attempt at ICSI. These same authors performed another study to try to relate the rate of sperm aneuploidy in eighteen men with OAT and the results of ICSI in affected couples. For these cases of OAT, and overall fertilization rate of 95% and a pregnancy of 39% was obtained. Very curiously, this pregnancy rate was significantly higher than reported by multiple centers practicing the ICSI technique (the generally accepted average rate is around 25%), which the authors of the article do not discuss. The rate of oocyte fertilization by ICSI was independent of the rate of aneuploidy. On the other hand, the patients who had not had a pregnancy (91%) had significantly higher aneuploidy rates than those of the controls.

Bernardini et al. also analyzed by FISH the rate of aneuploidy of the spermatozoa for chromosomes 1, 17, X, and Y, on a series of twenty-two cases of infertile men compared to fertile controls. A significantly higher rate of aneuploidy was found in men with OAT (18%) compared to controls (2.28%).

In the case of azoospermia patients, it is now sometimes possible to perform ICSI after a testicular biopsy in which sperm is found. The reported numbers of chromosomal abnormalities are impressive: indeed, one study estimated the proportion of chromosomal abnormalities at 19.6% in a group of patients with non-obstructive azoospermia and 8.2% in those with obstructive azoospermia. Here again, the link between gonadal insufficiency and the presence of chromosomal aneuploidies is well demonstrated.

It can be concluded from these data that a high rate of aneuploidy in spermatozoa is associated with a low rate of pregnancy and therefore less success through assisted reproduction by ICSI. However, the rate of fertilization of the oocytes does not seem to depend on the rate of aneuploidy, which means that the transferred embryos are more often carriers of aneuploidies and that on the other hand, their implantation would be disadvantaged. In this context, genetic counseling following a FISH analysis of the sperm would be highly desirable, before a couple begins a long and difficult procedure of assisted reproduction by ICSI.

SPERMATOZOID ANEUPLOIDS AND GENE FACTORS

A particularly important point of these studies is that they make it possible to explain certain male infertilities so far called “idiopathic”. In fact, disturbances of meiosis or premeiotic mitosis during spermatogenesis could predispose to the non-chromosomal disjunctions that are observed. The next step would consist in identifying which are the genetic factors at the origin of these disorders of meiosis and mitosis and to characterize them to have one more diagnostic means available in idiopathic male infertility. If gene abnormalities predisposing to non-disjunctions were detected, this diagnostic tool would be available and the possible transmission in the offspring of this pathology would be evaluable. And then supported by numerous studies. We now know that at least thirty genes are involved in the control of meiotic and mitotic divisions. For example, the role of HspA2, a “chaperone” protein with a specific testicular expression that is thought to be involved in the synaptonemal complex has recently been demonstrated. The role of genes of the MAD (Mitotic Arrest Deficiency) family involved in premeiotic mitotic control is also discussed.

There is a case, recently reported in the literature, where FISH analysis of spermatozoa made it possible to pose a contraindication to ART. In the study in question patients with different types of absolute teratospermia (100%) were studied. One of them had a sperm morphological abnormality consisting of macrocephaly and multiple flagella. In this patient, 90% of the sperm analyzed by FISH presented aneuploidy. This result was considered to be a contraindication to ICSI.

FEASIBILITY

In these various studies, between 3000 and 10,000 sperm per patient are analyzed. This represents a significant investment of time, considering that for FISH analysis on amniocytes, there are routinely between 50 and 100 cells. It is estimated that to detect significant levels of aneuploidy in sperm, an analysis of around 1000 cells may be sufficient. The method of collection is no different from that for a spermogram, and only a small fraction of ejaculate is used to smear onto slides for chemical treatment of the sample prior to FISH.

CONCLUSION

While the use of FISH on spermatozoa in male infertility appears undoubtedly valuable and contributory in the context of a pre-ART workup, or after repeated ART failures, the formal indications for this analysis have not yet been clearly established. established. One of the first uses of this approach could be to give couples undergoing a pre-ICSI procedure for OAT or azoospermia a more detailed indication of the chances of success and risks of miscarriages due to chromosomal abnormalities potentially present in the sperm. This information should then be communicated to patients within the framework of genetic counseling, taking into account the psychological repercussions of a possible poor prognosis of success.

Some authors also consider that this technique can be used in the event of miscarriages with repetitions of undetermined etiology beyond the framework of male infertility. Indeed, if 60% of the miscarriages of the first trimester are due to chromosomal abnormalities and a majority are of maternal origin, the FISH technique on the spermatozoa has shown a paternal origin in 8 to 12% of cases, corresponding to a greater incidence of chromosomal abnormalities in their gametes.

We deliver all over the world. 

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

OLIGO-ASTHENO-TERATOSPERMIA

You have been trying to have a baby for several months, but it is late. After tests, your doctor told you that your loved one has oligoasthenoteratospermia (OATS). What are OATS and what are the consequences? 

However, the experts at Dawasanté provide you with a natural treatment to permanently cure oligo- asthenoteratospermia.

Click HERE or on the image below to discover this natural treatment 

We deliver all over the world. 

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.

What is Oligoasthenoteratospermia or OATS?

OATS designates a set of abnormalities found during the spermogram during a male infertility assessment. The OATS groups together a low concentration of sperm (oligo) with therefore too few spermatozoa to naturally fertilize an oocyte, too low mobility of these spermatozoa (astheno) which does not allow them to join the oocyte and too large a proportion abnormal sperm (terato). However, OATS can present varying degrees. It can be severe, with very low mobility and concentration indices while the malformation index is very high. It can be moderate with indices closer to normal. Intermediate forms exist with indices of the same degree or which may be of different degrees: severe for one or two types of indices (eg: mobility and concentration) and moderate for the third.

What happens after diagnosis of the OATS?

Once the OATS is discovered, the doctor will look to determine if there are any causes for these abnormalities. Indeed, OATS can be reduced, at least in part, depending on its origin. He will look first for signs of infections, old or recent. Some infections, such as chlamydia,  can cause a decrease in male fertility. Their treatment can help regain better fertility. Likewise, the treatment of a  varicocele (varicose veins in one or both testicles) or stopping smoking may improve the results of a spermogram. Further research will be carried out to find out if there is a malformation in the testes or seminal tract. In all cases, a second spermogram will be done because it is possible that significant variations appear and allow to hope for other opportunities for natural fertilization.

What to do to have a child in the event of OATS?

If the diagnosis of OATS is confirmed, the possibility of natural fertilization is reduced. However, it does exist, especially if it is a moderate form. However, certain factors, such as the woman's age or the length of time contraception has been stopped must be taken into account and assisted reproduction (ART) may be considered. Depending on the case, it will be an in utero insemination (IUI) where the sperm is introduced directly into the uterus, and in vitro fertilization (IVF) where the sperm is brought into contact with one or more oocytes in the laboratory or an intracytoplasmic sperm injection (ICSI) where sperm is introduced directly into an oocyte in the laboratory. These different techniques will be offered depending on the degree of OATS. The success of IVF or ICSI is of the order of 25 to 30% which leaves hope to those who are concerned by this difficulty.

Asthenospermia is an abnormality of the sperm that is characterized by insufficient mobility while their number remains normal. Also called asthenozoospermia, this sperm fatigue is one of the possible causes of male fertility problems. What are the main causes? How is asthenospermia diagnosed? What treatment is there to promote procreation?

What is asthenospermia due to?

The main causes that can explain unsatisfactory sperm mobility are:

• a morphological anomaly of the male gametes,
• an infection,
• presence of anti-sperm antibodies
• medication,
• a  varicocele,
• a dietary deficiency,
• a renal failure,
• liver failure
• chemotherapy,
• exposure to radiation,
• excessive alcohol consumption,
• a deficiency in calcium,  vitamin D, or trace element ...

How is asthenospermia diagnosed?

A semen analysis, or spermogram, is used to assess the mobility of the sperm. It should be remembered that only mobile gametes can fertilize the egg. Many medical analysis laboratories rely on the classification decreed by the World Health Organization to classify spermatozoa:

• Level A (or I): progressive rapid sperm advance quickly and in a straight line,
• Level B (or II): the slow progressive spermatozoa advance slowly or in a curved line,
• Level C (or III): non-progressive spermatozoa move but do not progress,
• Level D (or IV): the sperm are immobile.

To be qualified as normal, the spermogram must show a minimum of 40% of motile spermatozoa and 32% of spermatozoa showing progressive mobility.

What solutions to have a child?

The management of asthenospermia varies mainly according to its origin. Thus, an infection will have to be treated according to its nature with appropriate antibiotic drugs while certain testicular abnormalities may, in some cases, be the subject of surgery. While there is no curative treatment for asthenospermia, certain drugs help improve the quality of sperm: vitamins, hormones, alternative medicine (herbal medicine, homeopathy, aromatherapy, etc.). When the treatments do not give satisfactory results, in vitro fertilization with donor sperm or an intracytoplasmic injection of sperm may be considered in the context of Medically Assisted Reproduction ( MAP).) when the couple wants a child.

We deliver all over the world. 

For more information, you can contact our experts on +229 51374202 direct line or by WhatsApp at the same number.